Registration Dossier
Registration Dossier
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EC number: 620-216-4 | CAS number: 298692-41-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2006-01-23 - 2006-07-19
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP-study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- isopropyl (diaminophosphoryl) carbamate
- Cas Number:
- 298692-41-8
- Molecular formula:
- C4H12N3O3P
- IUPAC Name:
- isopropyl (diaminophosphoryl) carbamate
- Details on test material:
- - Analytical purity: > 99%
- Lot/batch No.: S-6
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 72 h
- Post exposure observation period:
- no post exposure observation
Test conditions
- Hardness:
- NaHCO3: 50 mg/l
- Test temperature:
- 24 °C
- pH:
- 7.2 - 7.5
- Nominal and measured concentrations:
- nominal (mg/l): 100
measured (mg/l): 0 h: 101.8
96 h: 100.4 - Reference substance (positive control):
- no
Results and discussion
Effect concentrations
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- In the present study the test item in a concentration of 100 mg/l did not cause any inhibition in cell growth of algae. The EC50 (72hours) algae of the test item is greater than 100 mg/l. Based on the results of the reported study it is concluded that the test item is not acutely toxic to algae.
- Executive summary:
In the present study the test item in a concentration of 100 mg/l did not cause any inhibition in cell growth of algae. The EC50 (72hours) algae of the test item is greater than 100 mg/l. Based on the results of the reported study it is concluded that the test item is not acutely toxic to algae.
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