Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

Whereas absorption of aluminium hydroxide and other aluminium3+species via oral, dermal and inhalation pathways is considered low (in the range of 1 % and less) the opposite holds true for isopropanol with absorption rates of estimated 100% via oral and inhalation route and up to 8 % via dermal route. Thus, the toxicokinetics of aluminium tri-isopropanolate is dominated by the organic moiety isopropanol. Bioaccumulation is neither a concern for aluminium3+species nor for isopropanol (metabolism and excretion is efficient and rapid

Key value for chemical safety assessment

Bioaccumulation potential:
no bioaccumulation potential
Absorption rate - oral (%):
100
Absorption rate - dermal (%):
8
Absorption rate - inhalation (%):
100

Additional information

The complete toxicokinetic assessment is included in section 13 of IUCLID