Registration Dossier
Registration Dossier
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EC number: 412-720-6 | CAS number: 156653-67-7
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 11 March 1993 to 23 April 1993
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted to EU test guidance in compliance wtih GLP.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 993
- Report date:
- 1993
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- 84/449/EEC
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- flask method
Test material
- Details on test material:
- See below
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- 217 g/L
- Temp.:
- 30 °C
- pH:
- 4.5
- Details on results:
- The high percentage of inorganic salts present in the test substance (see project OC 018-93) possibly influences the solubility of Reaktiv-Gelb F-66923 in water. Therefore it was decided to perform the experiments with amounts lower than required in the guideline. (Requirement of the guideline: The study has to be performed with amounts 5 times higher than the water solubility determined by preliminary experiments.)
Within the error of the method, these results are independent of stirring time at 30 °C. An average can be calculated from these data.
Average: 402.34 g/l
Standard deviation: 8.12 g/
(rel. standard deviation: 2.0 %)
Any other information on results incl. tables
Experiment No. |
Portion test substance (g) |
Stirring time (h) at 30 °C |
pH at room temperature |
Mass ratio testsub-Avaler (g/1) ; |
1 |
25.08 |
24 |
4.5 |
400.85 |
2 |
25.11 |
48 |
4.5 |
411.10 |
3 |
25.08 |
72 |
4.5 |
395.07 |
4 (blank) |
0 |
72 |
6.3 |
0 |
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): very soluble (> 10000 mg/L)
Water solubility of the test substance (corrected to the purity of 54 % (w/w)):
Cs(Reaktiv-Gelb F-66923 FW) =217 g/l - Executive summary:
Study conducted to EU test guidance 84/449/EEC part A6 in compliance with GLP.
Water solubility of the test substance (corrected to the purity of 54 % (w/w)):
Cs(Reaktiv-Gelb F-66923 FW) =217 g/l
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