Slags, ferrochromium-manufg.

Endpoint summary

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion

Endpoint conclusion:

no adverse effect observed (not sensitising)

Additional information:

There are no reliable test reports on the skin sensitisation by silicates.

The amorphous glass phase of FeCr-slag consists of practically insoluble silicates, and therefore it is seen justified to use read-across to studies on different silicates.

Silicates have been evaluated as nonsentising by Cosmetic Ingredient Review Expert Panel, which was established by the industry trade association with the support of the U.S. Food and Drug Administration and the Consumer Federation of America. Although funded by the Council, CIR and the review process are independent from the Council and the cosmetics industry.

Several silicates have bee approved as food additives. Many silicates are also accepted as excipients in medicines.

No reliable reports on occupational sensitisations have been found.

In ferrochromium slag, chromium is in the trivalent form or as chromium metal, none of these forms showing any signs of causing sensitisation.

Migrated from Short description of key information:
No data are available on the sensitising potential of ferrochromium slag. Silicates have been in consumer use long and extensively as food additives, as excipients in medicines and as ingredients in cosmetics. No sensitising potentials have been seen. There are either no reports for sensitisation in occupational use. In ferrochromium slag, chromium is in the trivalent form or as chromium metal, none of these forms showing any signs of causing sensitisation.

Respiratory sensitisation

Endpoint conclusion

Additional information:

Migrated from Short description of key information:
No data are available on respiratory sensitisation.

Justification for classification or non-classification

There are no data indicating a need for silicates to be classified as sensitising, and therefore ferrochromium slag is not either suggested to be classified for sensitisation.

There are no reliable reports on the skin sensitisation by silicates. They have been evaluated as nonsentising by Cosmetic Ingredient Review Expert Panel, which was established by the industry trade association with the support of the U.S. Food and Drug Administration and the Consumer Federation of America. Although funded by the Council, CIR and the review process are independent from the Council and the cosmetics industry.

Several silicates have bee approved as food additives and excipients in medicines.

No reliable reports on occupational sensitisations have been found.

Chromium in ferrochromium slag is in the trivalent form, which does not cause sensitisation.