Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 212-146-4 | CAS number: 765-43-5
Endpoint summary
Administrative data
Description of key information
Skin corrosion Cat. 1B (H314) (covering Eye irritation Cat. 2).
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Two skin irritation studies showed slightly irritating effects on the rabbit skin. In another skin irritation study (OECD 404), strongly irritating effects were observed. These findings lead to classification as Skin Corr. Cat 1B according to the classification criteria of the Regulation (EC) No. 1272/2008 (CLP).
In a valid eye irritation study in the rabbit strongly irritating effects on the rabbit eye were observed.
Justification for selection of skin irritation / corrosion endpoint:
Please refer to discussion.
Justification for selection of eye irritation endpoint:
There is only one study available on eye irritation for this substance.
Effects on skin irritation/corrosion: corrosive
Effects on eye irritation: highly irritating
Justification for classification or non-classification
The substance is classified as Skin Corr. Cat 1B (H314) according to the classification criteria of the Regulation (EC) No. 1272/2008 (CLP).
Since H314 commumicates the more serve hazard to both skin and eye, the separate eys classification is not listed in section 2 of this dossier.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
