Registration Dossier
Registration Dossier
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EC number: 225-059-1 | CAS number: 4635-59-0
Endpoint summary
Administrative data
Description of key information
Additional information
In aquatic systems, 4 -chlorobutyryl chloride (CAS 4635 -59 -0) hydrolyses quickly and forms HCl (CAS 7647-01-0) and 4 -chlorobutyric acid (CAS 627 -00 -9) (for details see section 5.1.2).
Short-term toxicity to fish
Parent compound 4 -chlorobutyryl chloride: With high probability acutely not harmful to fish after pH-adjustment (96 -h LC50 > 100 mg/L, neutralized).
Hydrolysis product 4 -chlorobutyric acid: With high probability acutely not harmful to fish after pH-adjustment (depending on the results of the parent compound).
Hydrolysis product HCl: Acutely toxic to fish (pH dependent; 96-h LC50 = 4.92 mg/L).
Short-term toxicity to aquatic invertebrates
Parent compound 4 -chlorobutyryl chloride: No data available.
Hydrolysis product 4 -chlorobutyric acid: No data available.
Isobutyric acid: Acutely harmful to aquatic invertebrates (48 -h EC50 = 51.25 mg/L).
Hydrolysis product HCl: Acutely very toxic for aquatic invertebrates (pH dependent, 48 -h EC50 = 0.492 mg/L).
Toxicity to aquatic algae and cyanobacteria
Parent compound 4-chlorobutyryl chloride: No data available.
Hydrolysis product 4-chlorobutyric acid: No data available.
No data available for the parent compound and its hydrolysis product, therefore the short-term toxicity to aquatic algae and cyanobacteria is assessed on the results of the structurally similar substances 3-chloropropionic acid isobutyric acid.
Isobutyric acid: Acutely harmful to aquatic invertebrates (72 -h ErC50 = 50.6 mg/L and 72 -h NOErC = 32.5 mg/L; geometric mean).
Hydrolysis product HCl: Acutely very toxic for aquatic organisms (pH-dependent, 72 -h ErC50 = 0.492 mg/L).
Toxicity to microorganisms
Parent compound 4 -chlorobutyryl chloride: The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations (30 -min EC20 > 1000 mg/L).
Hydrolysis product 4 -chlorobutyric acid: No data available.
Hydrolysis product HCl: No data available.
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