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EC number: 246-186-9
CAS number: 24347-58-8
Montgomery et al. 1993 investigated the metabolism of the individual
isomers of 2,3 -butanediol (levo (2R,3R), dextro (2S,3S), meso 2,3
-butanediol and racemic 2,3 -butanediol) in perfused livers from fed
rats. Differences were observed in the metabolism of individual
2,3-butanediol isomers in perfused rat liver. Interconversion of isomers
and oxidation to acetoin was observed with the levo and meso forms, but
not with dextro 2,3-butanediol. In liver perfusions with either levo or
meso (radio-labelled) 2,3-butanediol, the substrates were converted to
labelled acetate, R-3-hydroxybutyrate and CO2, suggesting that
2,3-butanediol was oxidized to acetyl-CoA via acetoin.
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