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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
dissociation constant
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
Dissociating properties:
no
No.:
#1
pKa:
14.22
Remarks on result:
other: stongest acid
No.:
#2
pKa:
-3
Remarks on result:
other: strongest base
Conclusions:
pKa (Strongest Acidic) 14.22 (ChemAxon)
pKa (Strongest Basic) -3 (ChemAxon)
Executive summary:

Information was taken from the publicly accessible Human Metabolome Database (HMDB) - Metabocard for 2,3 -Butanediol (HMDB0003156):

- pKa (Strongest Acidic) 14.22 (ChemAxon)

- pKa (Strongest Basic) -3 (ChemAxon)

Source: http://www.hmdb.ca/metabolites/HMDB0003156 - accessed 14.06.2018.

Description of key information

pKa (Strongest Acidic) 14.22 (ChemAxon)

pKa (Strongest Basic) -3 (ChemAxon)

Key value for chemical safety assessment

pKa at 20°C:
14.22

Additional information

Information was taken from the publicly accessible Human Metabolome Database (HMDB) - Metabocard for 2,3 -Butanediol (HMDB0003156):

- pKa (Strongest Acidic) 14.22 (ChemAxon)

- pKa (Strongest Basic) -3 (ChemAxon)