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EC number: 253-462-2
CAS number: 37321-62-3
The hazard assessment is based on the data currently available.
New studies with the registered substance and/or other member substances
of the glycol esters category will be conducted in the future. The
finalised studies will be included in the technical dossier as soon as
they become available and the hazard assessment will be re-evaluated
For further details, please refer to the category concept document
attached to the category object (linked under IUCLID section 0.2)
showing an overview of the strategy for all substances within the glycol
Classification relevant information for environmental hazard:
Based on the results of the read across substances and the QSAR
predictions, the target substance dodecanoic acid, ester with
1,2-propanediol (CAS 37321 -62 -3) is considered readily biodegradable.
Aquatic acute toxicity
EL50 (48 h) = 6.59 mg/L (nominal, OECD 202)
EL50 (72 h) = 31.25 mg/L (nominal, OECD 201)
Aquatic chronic toxicity:
NOELR (72 h) = 9.76 mg/L (nominal, OECD 201)
Classification according to CLP
Based on the available data listed above, the most sensitive acute
effect concentration was obtained for aquatic invertebrates, with an
EL50 (48 h) of 6.59 mg/L (nominal). Thus, the substance does not need to
be classified for acute aquatic toxicity according to the consolidated
version of Regulation (EC) No 1272/2008 (CLP) and following amendments
The NOELR (72 h) = 9.76 mg/L (nominal) for algae is the only chronic
aquatic effect concentration available. As the substance is readily
biodegradable and the log Pow is 5.0 to >10, the substance need to be
classified for chronic aquatic toxicity according to the Regulation (EC)
No 1272/2008 (CLP) and following amendments (ATPs) as Aquatic Chronic 2.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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