Registration Dossier
Registration Dossier
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EC number: 265-929-8 | CAS number: 65799-47-5
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2014-12-15 to 2015-02-04
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7200 (Melting Point / Melting Range)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- method to determine freezing temperature
- Key result
- Melting / freezing pt.:
- < -80 °C
- Atm. press.:
- 1 013 hPa
- Conclusions:
- A melting point value of <-80°C was determined in a reliable study conducted according to an appropriate test protocol, and in compliance with GLP.
Reference
Description of key information
Melting point: <-80°C at 1013 hPa (OECD 102) by read-across from structural analogue.
Key value for chemical safety assessment
Additional information
There is no measured melting/freezing point for the submission (target) substance. Therefore, good quality data were read-across from a structural analogue, [3-(2,3-epoxypropoxy)propyl]diethoxy(methyl)silane (source substance). The source and target substances are both dialkoxysilanes with 3-(2,3-epoxypropoxy)propyl and methyl side-chains. The difference between these substances is that the two alkoxy groups are ethoxy for the source substance and methoxy for the target substance. The source substance has a higher molecular weight than the target substance and as a result, the melting/freezing point of the source substance is expected to be higher than that of the target substance. A melting point value of <-80°C was determined for [3-(2,3-epoxypropoxy)propyl]diethoxy(methyl)silane in a reliable study conducted according to an appropriate test protocol, and in compliance with GLP. The result is considered to be reliable and is read-across to the submission substance, [3-(2,3-epoxypropoxy)propyl]dimethoxy(methyl)silane.
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