Registration Dossier
Registration Dossier
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EC number: 222-048-3 | CAS number: 3327-22-8
Endpoint summary
Administrative data
Description of key information
The key skin sensitisation study, a reliable adjuvant study conducted according to OECD 406, found that the test material (as supplied, 69% CHPTAC) gave no evidence of sensitisation potential during a subsequent challenge with a 30% solution of the test material in saline.
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
In a dermal sensitization study (OECD 406) with CHPTAC (69% aqueous solution), young adult female guinea-pigs of the Dunkin-Hartley strain were tested using the method of Magnusson and Kligman. No dermal reactions were seen when challenging with a 30% solution of the test material in saline. In this study, CHPTAC (69%) is not a dermal sensitizer.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
In a dermal sensitisation study according to OECD 406, female guinea pigs were tested negative for CHPTAC (69%). Based on the results, no classification for CHPTAC (69%) is warranted.
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