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EC number: 222-048-3
CAS number: 3327-22-8
Highest test concentration (9.3 g/l QUAB) caused no effects
on the Dehydogenaseactivity of the sludge. As the QUAB
contains ca. 55 %
3-Chloro-2-hydroxypropyl)trimethylammoniumchloride, the more
correct test concentration would be 5.115 g/l.
No EC50-value could be found with the highest test
concentration of 2000 mg/l. In the test report EC20-, EC50 -
and EC80-values higher than 2000 mg/l have been reported,
but no EC10-value has been estimated. Based on graphical
estimation EC10-value of 1225 mg/l can be extrapolated.
There were no estimations of goodness of fit parameters
available in graphs (standard deviation, R2 etc.)
In the addendum to the test report EC10-value has been
estimated to be 1032 mg/l.
At the highest concentration tested (32 g/l) a growth
inhibition of 10% was found. The toxicity threshold was,
therefore 32 g/l. According to the test report from these
data an EC50 of 58 g/l with respect to the growth rate was extrapolated.
The key study to assess toxicity towards
microorganisms was conducted according to OECD 209 and GLP. The EC10 was
determined with 1032 mg/L.
Besides the key study several information
sources are reported indictating that CHPTAC is not toxic to
microorganisms. Read-across information from the Diol is included in the
present dossier as it is the main degradation product taken into account
in the EU Risk Assessment Report on CHPTAC (2008). An EC10 of 32g/L was
determined for the diol.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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