Registration Dossier
Registration Dossier
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EC number: 236-599-2 | CAS number: 13446-49-6
Genetic toxicity: in vivo
Administrative data
- Endpoint:
- in vivo mammalian germ cell study: cytogenicity / chromosome aberration
- Remarks:
- Type of genotoxicity: chromosome aberration
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- significant methodological deficiencies
- Remarks:
- Several shortcomings (e.g): - Test subtance not adequately described - Insufficient methodical details
Data source
Reference
- Reference Type:
- publication
- Title:
- Mutachromosomal effects of some trace elemants on mammalian systems
- Author:
- Giri, A.K. et al.
- Year:
- 1 981
- Bibliographic source:
- Bionature, 1 (1&2): 55-58
Materials and methods
- GLP compliance:
- no
- Type of assay:
- chromosome aberration assay
Test material
- Reference substance name:
- Disodium molybdate
- EC Number:
- 231-551-7
- EC Name:
- Disodium molybdate
- Details on test material:
- - Name of test material (as cited in study report): Sodium molybdate (Na2MoO4)
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- male
Administration / exposure
- Route of administration:
- oral: gavage
- Duration of treatment / exposure:
- 21 days
Results and discussion
Test results
- Sex:
- male
- Genotoxicity:
- positive
Applicant's summary and conclusion
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