Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Skin irritation: non-irritant
Eye irritation: Minimal irritant

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

Acute irritation studies were performed on the skin and eye of rabbits.

Skin irritation/corrosion: There was no skin irritation at any test site on any animal during th 4 hours exposure of the study. The primary irritation index for the test material was 0/8.0.

Eye irritation: Slight to mild conjunctivitis was noted 1 hour post dosing. Within 24 hours all irritation had resolved and the test was terminated following the 72 hour scoring. Under the conditions of the test the test material is judged to be minimally irritating.


Effects on eye irritation: slightly irritating

Justification for classification or non-classification

Based on the experimental results of the Acute skin and eye irritation studies and according to the EEC criteria for classification and labelling requirements for dangerous substances and preparations (Guidelines in Commission Directive 93/21/EEC, 27th April 1993), FR-370 does not have to be classified and has no obligatory labelling requirement for skin irritation or eye irritation.