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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
February from 4th to 10th, 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
Adopted 27th July 1995
Deviations:
yes
Remarks:
not impacting the test results
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
yes
Remarks:
not impacting the test results
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Water solubility:
400 - 500 g/L
Temp.:
20 °C
Remarks on result:
other: The pH has not been measured due to the high viscosity of the mixtures.
Details on results:
40.00 g of the test substance was dissolved in 100 ml of redistilled water. It corresponds to the concentration 400 g/l. 50.00 g of the test substance was not dissolved in 100 ml of redistilled water. Test substance particles did not settled down after 15 minutes of centrifugation at 3000 RPM. The viscosity did not allow separating the solid particles from the liquid. Further testing was not done due to the high viscosity of the mixtures.
It is not possible to determine absolute test substance water solubility by flask method due to the high viscosity of the test substance mixture with water.
Based on the microscopy observation, the water solubility of the test substanc should be between 400 - 500 g/l.
Conclusions:
Water solubility: 400 - 500 g/l at 2 °C
Executive summary:

Water solubility test was performed for the test substance., using the flask method was used. Test was performed according to the Method A.6. and OECD guideline 105.

It was not possible to determine absolute water solubility of test substance in water by flask method due to the high viscosity of saturated solution. Expected solubility in water should be between 400 - 500 g/l.

Conclusion

Water solubility: 400 - 500 g/l at 2 °C.

Description of key information

Water solubility: 400 - 500 g/l at 20 °C

Key value for chemical safety assessment

Water solubility:
400 g/L
at the temperature of:
20 °C

Additional information

Flask method - OECD 105