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EC number: 943-024-5
CAS number: -
See attached tables
The potential of Sodium toluene 4-sulphonate to cause effects on the reproductive performance of male and female was assessed following official guideline OECD 421, Reproduction/Developmental Toxicity Screening Test. In this screening study the substance was administered to male and female Sprague-Dawley rats (12 animals/sex/dose) by oral gavage at dose levels of 0, 100, 300 or 1000 mg/kg bw/day. Males and females in the 1000 mg/kg bw/day group showed diarrhea or soft feces, and males showed mild inflammatory cell infiltration of the lamina propria and squamous cell hyperplasia in the limiting ridge of the stomach. There were no effects from administration of the substance in the reproductive function or development and growth of the next generation in any dose group.
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