Registration Dossier
Registration Dossier
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EC number: 210-817-6 | CAS number: 623-84-7
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A 48-hr Acute Toxicity Test with Daphnia magna was conducted with PGDA. The test conduct followed OECD Guideline 202 and met GLP
requirements. The 48-hr EC50 was determined to be 237 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 237 mg/L
Additional information
A short-term aquatic invertebrate toxicity test was conducted with the freshwater cladoceran, Daphnia magna for 48 -hrs exposed to propane-1,2 -diyl diacetate (PGDA) with endpoints consisiting of immobilization and mortality. The test followed OECD 202, met GLP requirements and therefore was consider the key study with a Klimisch score of 1. Test concentrations were set at 32, 56, 100, 180, 320, 560 and 1000 mg/L with a laboratory water control (DSW). The 48 -hr LC50 and EC50 values were both 237 mg/L (C.I. 207 - 294). The No Observed Effect Concentration was 100 mg/L.
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