Registration Dossier
Registration Dossier
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EC number: 273-794-1 | CAS number: 69029-48-7 Product from the pH-adjustment of indium-rich solutions causing the precipitation of indium, ammonium and cadmium hydroxides and sulfates and zinc sulfate.
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- other: software
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
- Principles of method if other than guideline:
- Acute toxicity of UVCB substance was determined by classifying based on Mixture rules from EU CLP (tier 2=summation of classified components to derive Hazard class)
- GLP compliance:
- no
- Remarks:
- equivalent quality assurance
- Type of assay:
- other: CLP caclulation software
Test material
- Reference substance name:
- Indium, cake
- EC Number:
- 273-794-1
- EC Name:
- Indium, cake
- Cas Number:
- 69029-48-7
- IUPAC Name:
- Insoluble indium-containing residue after precipitation of indium bearing solutions
Constituent 1
Results and discussion
- Remarks on result:
- not measured/tested
- Remarks:
- prediction
Any other information on results incl. tables
The calculated classification via mixture toxicity resulted in a "germ cell mutagenicity Cat 1B" classification for the UVCB substance (toxicity of all metal constituents are known from 9th ATP CLP + all assessed metals). The result is mainly driven by Cd.
Applicant's summary and conclusion
- Conclusions:
- Good quality study that can be used to derive classification of the UVCB substance and predict hazard. Note toxicities of constituents/species as of 9th ATP CLP + assessed metals
- Executive summary:
The calculated classification via mixture toxicity resulted in a "germ cell mutagenicity Cat 1B" classification for the UVCB substance (toxicity of all metal constituents are known from 9th ATP CLP + all assessed metals). The result is mainly driven by Cd.
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