Registration Dossier
Registration Dossier
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EC number: 273-794-1 | CAS number: 69029-48-7 Product from the pH-adjustment of indium-rich solutions causing the precipitation of indium, ammonium and cadmium hydroxides and sulfates and zinc sulfate.
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- other: software
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
- Principles of method if other than guideline:
- Acute toxicity of UVCB substance was determined by classifying based on Mixture rules from EU CLP (tier 2=summation of classified components to derive Hazard class) and back calculation to the corresponding L(E)C50 range
- GLP compliance:
- no
- Remarks:
- equivalent quality assurance
Test material
- Reference substance name:
- Indium, cake
- EC Number:
- 273-794-1
- EC Name:
- Indium, cake
- Cas Number:
- 69029-48-7
- IUPAC Name:
- Insoluble indium-containing residue after precipitation of indium bearing solutions
Constituent 1
Test animals
- Species:
- other: standard species relevant to acute toxicity classification
Results and discussion
Effect levelsopen allclose all
- Dose descriptor:
- LC50
- Effect level:
- > 0.05 - <= 0.5 other: mg/l
- Based on:
- dissolved
- Remarks on result:
- other: prevision worst case
- Dose descriptor:
- LC50
- Effect level:
- > 0.5 - <= 1 other: mg/l
- Based on:
- dissolved
- Remarks on result:
- other: prevision typical
Any other information on results incl. tables
The calculated classification via additivity method resulted in an "acute inhalation toxicity cat 3" classification for the typical sample and category 2 for the worst case UVCB substance (toxicity of all metal constituents are known from 9th ATP CLP + all assessed metals). The result of typical is mainly driven by Pb, Cd, the result for the boundary is mainly driven by Pb compounds, Cd.
Applicant's summary and conclusion
- Interpretation of results:
- Category 2 based on GHS criteria
- Conclusions:
- Good quality study that can be used to derive classification of the UVCB substance and predict hazard.
- Executive summary:
The study provided a conservative estimate of the acute inhalation toxicity:
classification of typical is acute inhalation category 3
classification of worst case is acute inhalation category 2
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