Registration Dossier
Registration Dossier
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EC number: 435-410-2 | CAS number: 351491-23-1
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 02 May 2000 to 23 August 2000
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to other study
- Reason / purpose for cross-reference:
- reference to other study
- Reason / purpose for cross-reference:
- reference to other study
- Reason / purpose for cross-reference:
- reference to other study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- flask method
- Water solubility:
- 355.7 mg/L
- Incubation duration:
- 1 h
- Temp.:
- 20 °C
- Remarks on result:
- other: preliminary test
- Water solubility:
- 342 mg/L
- Incubation duration:
- 24 h
- Temp.:
- 20 °C
- pH:
- 4.5
- Water solubility:
- 356 mg/L
- Incubation duration:
- 48 h
- Temp.:
- 20 °C
- pH:
- 6.5
- Key result
- Water solubility:
- 354 mg/L
- Incubation duration:
- 72 h
- Temp.:
- 20 °C
- pH:
- 3.7
- Conclusions:
- The water solubility of the test item is 351 mg/l +/-8mg/l at 20°C and pH 3.7.
- Executive summary:
The test item water solubility was determined with the flask method according to recognised guideline and under GLP. No deviation from the guideline was observed in the study.
The water solubility of the test item is 351 mg/l +/-8mg/l at 20°C and pH 3.7.
Reference
Description of key information
The water solubility of the test item was determined in an experimental key study of Klimisch validity 1.
Key value for chemical safety assessment
- Water solubility:
- 351 mg/L
- at the temperature of:
- 20 °C
Additional information
The water solubility was determined at pH 3.7
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