Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-180-8 | CAS number: 92-70-6
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 3 (not reliable)
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Skin Irritation / Corrosion
- Author:
- SIDS OECD 2004
- Year:
- 2 004
- Bibliographic source:
- SIDS OECD 2004
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- GLP compliance:
- no
Test material
- Reference substance name:
- 3-hydroxy-2-naphthoic acid
- EC Number:
- 202-180-8
- EC Name:
- 3-hydroxy-2-naphthoic acid
- Cas Number:
- 92-70-6
- Molecular formula:
- C11H8O3
- IUPAC Name:
- 3-hydroxy-2-naphthoic acid
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
Test system
- Type of coverage:
- semiocclusive
- Preparation of test site:
- not specified
- Vehicle:
- other: polyethylene glycol
- Duration of treatment / exposure:
- 4 hours
- Observation period:
- 24 hours
- Number of animals:
- 3
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Time point:
- other: 24 h
- Reversibility:
- no data
- Remarks on result:
- other: no data concerning score
Applicant's summary and conclusion
- Interpretation of results:
- slightly irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Moistened 3-hydroxy-2-naphthoic acid was slightly irritating to the skin of rabbits in a test
performed according to OECD TG 404.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
