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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
grey literature
Title:
Pharmacological Properties of a New Diuretic: 5-Chloro-2,4-bis-Sulphonamidoaniline (Salamid)
Year:
1959
Bibliographic source:
Acta pharmacol. et toxicol. 1959, 15, 300-306
Report date:
1959

Materials and methods

Principles of method if other than guideline:
No data on method is available.
GLP compliance:
not specified
Test type:
other: no data

Test material

Constituent 1
Chemical structure
Reference substance name:
4-amino-6-chlorobenzene-1,3-disulphonamide
EC Number:
204-463-1
EC Name:
4-amino-6-chlorobenzene-1,3-disulphonamide
Cas Number:
121-30-2
Molecular formula:
C6H8ClN3O4S2
IUPAC Name:
4-amino-6-chlorobenzene-1,3-disulfonamide

Test animals

Species:
other: mouse and rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Doses:
about 10 g per kg bw

Results and discussion

Any other information on results incl. tables

The administered dose of 10 g/kg bw do not induce any signs of intoxication.

Applicant's summary and conclusion

Interpretation of results:
practically nontoxic
Remarks:
Migrated information
Conclusions:
The acute toxicity of the substance is very low.