Registration Dossier
Registration Dossier
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EC number: 221-221-0 | CAS number: 3033-77-0
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The main test was performed with nominal concentrations. No EC50-value could be detected with the highest concentration tested i.e. ErC50 was higher than 1000 mg/L. Graphically evaluated EC10 was 814 mg/L based on growth rate and the NOEC was 580 mg/L. Thus EPTAC is not toxic to Algae
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 1 000 mg/L
- EC10 or NOEC for freshwater algae:
- 580 mg/L
Additional information
A study on green algae Desmodesmus subspicatus (renamed, former name Scenedesmus subspicatus) was performed in 2003. The stability of the test substance was checked before the main test by measuring the concentrations of the substance, without the algae, after 0 and 72 hours. Concentrations deviated only slightly (less than 20%) from each other. Therefore, the main test was performed with nominal concentrations. No EC50-value could be detected with the highest concentration tested i.e. ErC50 was higher than 1000 mg/L. Graphically evaluated EC10 was 814 mg/L based on growth rate and the NOEC was 580 mg/L.
Two short term algae studies with nominal concentrations are available. EbC50-value of 23.8 mg/l and ErC50-value of 37.8 mg/l for Chlorella vulgaris have been reported (Degussa, 1991). However, the validity criteria of the study were not fulfilled, because the cell concentration in the control cultures was not increased by a factor of at least 16 within three days. The cell concentration in the controls within three days was 66-88 % of the required concentration. Therefore the results from the study will not be used in the risk assessment.
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