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Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
6 August to 21 Novemver 2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study conducted to current test guidelines in accordance with GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
yes
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate
EC Number:
411-700-4
EC Name:
1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate
Cas Number:
140921-24-0
Molecular formula:
C32H62N4O6
IUPAC Name:
2-[3-(heptan-3-yl)-1,2-oxazolidin-2-yl]ethyl N-{6-[({2-[3-(heptan-3-yl)-1,2-oxazolidin-2-yl]ethoxy}carbonyl)amino]hexyl}carbamate

Results and discussion

Water solubility
Water solubility:
< 0.97 mg/L
Temp.:
20 °C
pH:
6.7

Any other information on results incl. tables

After the stirring period, undissolved test substance was observed in the test sample. From this, it was concluded that the water solubility of 1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)- carbamate at 20 °C was <0.97 mg/l.

Some decomposition of the test substance likely had occurred during the test, but this cannot be avoided due to the nature of a water solubility study. Therefore this result was accepted as the best possible.

The pH of the aqueous sample was 6.7.

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): other: Insoluble (<1mg/l)
The water solubility at 20 °C was <0.97 mg/l.
Executive summary:

The water solubility was measured according to the OECD Guideline 105. The water solubility was visually determined. Due to the instability of the test substance in water it was not possible to develop a quantitative method. After the stirring period, undissolved test substance was observed in the test sample. From this, it was concluded that the water solubility of 1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)- carbamate at 20 °C was <0.97 mg/l.

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