Registration Dossier
Registration Dossier
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EC number: 268-610-1 | CAS number: 68131-13-5
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- October 4-7, 2010
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Naphthenic acids, reaction products with diethylenetriamine
- EC Number:
- 268-610-1
- EC Name:
- Naphthenic acids, reaction products with diethylenetriamine
- Cas Number:
- 68131-13-5
- Molecular formula:
- C16H21N3O2 (minimal)
- IUPAC Name:
- Naphthenic acids, reaction products with diethylenetriamine
- Details on test material:
- Test substance: MK195K
Stability: No particular stability concerns
Solubility: Insoluble
Odor: Aromatic
Storage: room temperature
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 234 mg/L; 31mg/L as CaCO3
- Test temperature:
- 19.7-20.3°C at 48h
- pH:
- 7.7-7.8
- Dissolved oxygen:
- 9.2-9.3 at 48h
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 2.9 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: 95%CL (2.3-3.7mg/L)
Any other information on results incl. tables
MK195K was insoluble in seawater; upon addition to seawater in the mixing jars the majority of the material would float or be caught up in the stirring vortex.
During the 48 hour course of the study, normal behavior was observed in the control(s).
A twenty four hours of exposure, mortality of one test organism was observed at 1.25mg/L. Complete immmobilization (100%) was observed in the top concentration of 10mg/L, complete mortality was observed in all replicates.
The 48 hour EC50 and 95% confidence limits for MK195K to Daphnia magna were determined to be 2.9mg/L.
Applicant's summary and conclusion
- Conclusions:
- The 48 hour EC50 and 95% confidence limits for MK195K to Daphnia magna were determined to be 2.9mg/L.
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