Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 915-152-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
All the data available on reaction mass of lanthanum phosphate and cerium phosphate and terbium phosphate were quoted as reliability 1 according to Klimisch criteria and flagged as key studies. Only the data used in a read-across approach to conclude on chronic aquatic toxicity were scored with a reliability 2 and flagged as supporting studies.
Short-term toxicity to fish:
The acute toxicity of reaction mass of lanthanum phosphate and cerium phosphate and terbium phosphate to rainbow trout (Oncorhynchus mykiss) was determined in a 96-hour semi-static test according to the EU Commission Directive 92/69/EEC, Part C.1 (1992), and the OECD Guideline for Testing of Chemicals No. 203 (1992). Rainbow trouts were exposed to control and test chemical at a nominal loading rate of 100 mg/L. The test fish were observed after approximately 3, 24, 48, 72 and 96 hours test duration for mortality and visible abnormalities.
No mortality or visible abnormalities were determined in the control and at the loading rate of 100 mg/L during the 96h-period.
The 96-hour NOELR and the 96-hour LL0 of reaction mass of lanthanum phosphate and cerium phosphate and terbium phosphate to rainbow trout were determined to be ≥ 100 mg/L (measured test item concentration of 264 μg/L). The 96-hour LOELR, the 96-hour LL50 and 96-hour LL100 were > 100 mg/L or higher than mean measured test item concentration of 264 μg/L.
Short-term toxicity to aquatic invertebrates:
The acute toxicity of reaction mass of lanthanum phosphate and cerium phosphate and terbium phosphate to Daphnia magna was determined in a 48-hour static test according to the EU Commission Directive 92/69/EEC, Part C.2 (1992) and the OECD Guideline for Testing of Chemicals, No. 202 (2004). Daphnids were exposed to control and test chemical at a nominal loading rate of 100 mg/L for 48 hr (mean measured concentration of 45 µg/L). Mortality/immobilization were observed daily.
In the control and at the loading rate of 100 mg/L, no immobilized test organisms were determined during the test period of 48 hours. The 48 hour LL50 and NOELR were thus > 100 mg/L and ≥ 100 mg/L, respectively.
Toxicity to aquatic algae:
In a 72 hour acute toxicity study, the cultures of green algal species Scenedesmus subspicatus were exposed to reaction mass of lanthanum phosphate and cerium phosphate and terbium phosphate at the loading rate of 100 mg/L under static conditions in accordance with the EU Commission Directive 92/69/EEC, C.3 (1992), and the OECD Guideline 201 (2006).
Reaction mass of lanthanum phosphate and cerium phosphate and terbium phosphate had no toxic effect on Scenedesmus subspicatus up to the highest concentration which could be tested at a loading rate of 100 mg/L (corresponding to a mean measured concentration of 42 µg/L). The NOELR , the LOELR and EL50 values based on the growth (AUC, growth rate and yield) were ≥ 100 mg/L, > 100 mg/L and > 100 mg/L, respectively.
Toxicity to micro-organisms:
The activated sludge respiration inhibition test was waived according to column 2 of Annex VIII of REACH regulation as reaction mass of lanthanum phosphate and cerium phosphate and terbium phosphate is highly insoluble in water (2.06 µg/L at 20°C, RCC Study n° B39150, 2008, GLP), so that microbial toxicity is unlikely to occur.
Long-term aquatic toxicity:
Reaction mass of lanthanum phosphate and cerium phosphate and terbium phosphate is highly insoluble and presents no acute aquatic ecotoxicity. Furthermore, two supporting studies were provided in order to show that the insoluble compounds of cerium and lanthanum show no chronic toxicity to daphnids reproduction and survival up to and including the water solubility limit. From these data, it can be expected that the insoluble reaction mass of lanthanum phosphate and cerium phosphate and terbium phosphate should present a similar absence of long-term aquatic toxicity. From these elements and in accordance with the REACH principle intended to limit vertebrate testing (in the case of the fish test waiving), the chronic toxicity studies on fish and daphnids were waived.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
