Registration Dossier
Registration Dossier
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EC number: 204-820-1 | CAS number: 127-06-0
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
For the algae,Scenedesmus capricornutum, the 72-h EC50 was 11.8 mg/L, based on growth. The 72-hr NOEC was 2.56 mg/L, based on growth.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 11.8 mg/L
- EC10 or NOEC for freshwater algae:
- 2.56 mg/L
Additional information
A reliable toxicity study with algae is not available for acetone oxime. However, a reliable (Klimisch 1) toxicity study with algae has been conducted the analogue, butanone oxime and is included in this dossier.
Kurume Laboratory (1998) conducted a reliable (Klimisch 1) GLP compliant study following OECD 201 methods with the analogue, butanone oxime. The algae,Scenedesmus capricornutum, were exposed to the test substance at nominal concentrations of 1.02, 2.56, 6.4, 16 and 40 mg/L for 72 hrs under static conditions. The 72-h EC50 was 11.8 mg/L, based on growth. The 72-hr NOEC was 2.56 mg/L, based on growth. Consequently these values will be taken as the toxicity in algae endpoint for acetone oxime.
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