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Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

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Administrative data

Link to relevant study record(s)

Description of key information

Readily biodegradable: 85.2% (ThCO2) in 28 days (OECD 301B) (read-across)

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

No studies are available on the biodegradation of Reaction products of oleoyl sarcosine with sodium hydroxide. Therefore, data from the corresponding acid, (Z)-N-methyl-N-(1-oxo-9-octadecenyl)glycine (CAS 110-25-8), are used as read across. This read across approach is in accordance with Regulation (EC) No 1907/2006, Annex XI, 1.5. Grouping of substance and read across approach as is explained within the category justification in IUCLID Section 13. Except for different cations (hydrogen vs. sodium) the anions of both the source and target substance have similar chemical structures. Since dissociation of the sodium salt under environmental conditions (pH 4 - 9) yields the same ionic species as dissociation of the acidic form of the substance, this read across can be considered as justified.

Ready biodegradation of the read-across substance (Z)-N-methyl-N-(1-oxo-9-octadecenyl) glycine (CAS 110-25-8) was investigated in one study according to OECD 301B and GLP (Paulus, 2005) using domestic activated sludge as inoculum. Based on CO2 evolution, the substance attained 85.2% degradation after 28 days, fulfilling the 10-day window and can thus be classified as readily biodegradable according to the strict OECD criteria.

Based on the results from one structurally related read-across substance (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5.) it can be concluded that Reaction products of oleoyl sarcosine with sodium hydroxide is readily biodegradable according to the OECD criteria.