C-C1

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

3rd April 2007 to 26th April 2007

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of relevant results

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2007

Report date:

2007

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

GLP compliance:

yes

Remarks:

Date of inspection: 30th August 2005 Date of signature: 21st November 2005

Type of method:

effusion method: vapour pressure balance

Test material

Reference

Name:

Unnamed

Type:

Constituent

Details on test material:

Sponsor's identification :C-C1
Description : dark blue powder
Lot number : MB-1
Date received : 05 March 2007
Storage conditions :room temperature, in the dark, stored over silica gel

Results and discussion

Vapour pressure

Temp.:

ca. 25 °C

Vapour pressure:

0 Pa

Remarks on result:

other: First vapour pressure

Any other information on results incl. tables

No statistical analyses were performed because the balance readings were too low and variable for a line of best fit to have any meaning. Instead it was considered more appropriate to impose a regression slope on a chosen data point to provide an estimate of the maximum value for the vapour pressure at 25ºC.

Run 6 was chosen because the sample had been under vacuum for the longest period prior to this run and so degassing would have been the most complete. The reading at 249ºC (522.15 K) was chosen because this is the data point which gives the highest estimated vapour pressure at any given temperature when a slope of –1500 K is imposed upon it.

The value of –1500 K is an in-house value and is the shallowest slope observed whilst determining the vapour pressure on a wide range of samples using the vapour pressure balance method. Extrapolation to 25ºC gave a vapour pressure of 3.134 x 10^-5Pa which has been taken as a maximum for this material.

The test material did not change in appearance under the conditions used in the determination.

Applicant's summary and conclusion

Conclusions:

The vapour pressure of the test material has been determined to be less than 3.2 x 10-5 Pa at 25ºC.

Executive summary:

The vapour pressure was determined using a vapour pressure balance with measurements being made at several temperatures and linear regression analysis used to calculate the vapour pressure at 25°C. Testing was conducted using Method A4 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC), and in accordance with Method 104 specified in the OECD Guidelines for Testing of Chemicals, 25 March 2006.

The vapour pressure of the test material has been determined to be less than 3.2 x 10^-5Pa at 25ºC.