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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study according to OECD 107

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1997
Report date:
1997

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7550 (Partition Coefficient, n-octanol / H2O, Shake Flask Method)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
427-720-1
EC Name:
-
Cas Number:
26364-65-8
Molecular formula:
C4H5N3S
IUPAC Name:
[(1,3-thiazolidin-2-ylidene)amino]formonitrile
Details on test material:
name: Cyanamide, (4,5-dihydroxy-2-thiazolyl)-
molecular formula: C4 H5 N3 S
molecular weight: 127.2
physical state: solid
analytical purity: 99.8 %

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficientopen allclose all
Type:
log Pow
Partition coefficient:
-0.065
Temp.:
20 °C
Remarks on result:
other: unbuffered solution
Type:
log Pow
Partition coefficient:
-0.06
Temp.:
20 °C
pH:
4
Type:
log Pow
Partition coefficient:
-0.041
Temp.:
20 °C
pH:
7
Type:
log Pow
Partition coefficient:
-0.143
Temp.:
20 °C
pH:
9
Type:
Pow
Partition coefficient:
0.86
Temp.:
20 °C
Remarks on result:
other: unbuffered solution
Type:
Pow
Partition coefficient:
0.87
Temp.:
20 °C
pH:
4
Type:
Pow
Partition coefficient:
0.91
Temp.:
20 °C
pH:
7
Type:
Pow
Partition coefficient:
0.72
Temp.:
20 °C
pH:
9

Applicant's summary and conclusion

Conclusions:
The determination of the partition coefficient of the test substance in octanol-water indicate that there is not bioaccumulation potentiat for the test substance.
Executive summary:

The values found fpr CIT are summarized by the following table:

unbuffered pH4 pH7 pH9
Pow 0.86 0.87 0.91 0.72
log Pow - 0.065 - 0.060 - 0.041 -0.143