Registration Dossier
Registration Dossier
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EC number: 448-060-0 | CAS number: 727678-39-9
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no hazard identified
Marine water
- Hazard assessment conclusion:
- no hazard identified
STP
- Hazard assessment conclusion:
- no hazard identified
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- PNEC oral
- PNEC value:
- 333.3 mg/kg food
- Assessment factor:
- 300
Additional information
Conclusion on classification
Classification related key information
Water solubility: < 0.08 mg/L
Biodegradation in water: screening tests: 9% (ThCO2) after 29 days (OECD 301B)
Log Pow: 8.8
Acute toxicity
- to fish: No effects were observed up to the limit of water solubility of the test substance (measured concentration in test media was 0.043 mg/L), Cyprinus carpio (OECD 203, EU Method C.1)
- to aquatic invertebrazes: No effects were observed up to the limit of
water solubility of the test substance (measured concentration in test media was
0.041 mg/L), Daphnia magna (OECD 202, EU Method C.2)- to algae: No effects were observed in the range of the water solubility of the test substance (measured concentration in test media was
0.02 mg/L), Pseudokirchneriella subcapitata (OECD 201, EU Method C.3)
Chronic toxicity:
- to fish: not available
- to crustacea: not available
- to algae: No effects were observed in the range of the water solubility of the test substance (0.02 mg/L), Pseudokirchneriella subcapitata (OECD 201, EU Method C.3).
Classification justification according to CLP
2-[2-(3-butoxypropyl)-1,1-dioxo-1,2,4-benzothiadiazin-3yl]-5'-tert-butyl-2-(5,5-dimethyl-2,4 -dioxo-1,3-oxazolidin-3-yl)- 2'-[(2-ethylhexyl)thio]acetanilide (UY-330) shows no effects in acute tests with aquatic organisms (fish, daphnid, algae) in the range of its water
solubility (< 0.08 mg/L). Nevertheless, since the substance is not rapidly biodegradable and exhibits a substantial potential for bioaccumulation (log Pow 8.80), UY-330 is classified as environmental hazard Chronic Cat. 4 according to the regulation (EC) No. 1272/2008 (CLP) and the Regulation (EU) No. 286/2011 (2nd ATP).
Classification justification according to DSD
For fish, daphnid and algae, no effects were observed in the range of the water solubility of UY-330 (< 0.08 mg/L).
Based on the data above, the substance is considered to have a substantial potential for bioaccumulation and is not rapidly. degradable. Therefore, UY-330 is classified as environmental hazard R53 according to the Directive 67/548/EEC.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
