By-product from Guanidinoacetic acid manufacturing

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

temperature of decomposition (state purity)

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Qualifier:

equivalent or similar to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

GLP compliance:

no

Type of method:

differential scanning calorimetry

Specific details on test material used for the study:

Lot 201009MA2 solid

Key result

Atm. press.:

ca. 166 Bar

Decomposition:

yes

Decomp. temp.:

ca. 348 °C

Conclusions:

The substance "By-product from Guanidinoacetic acid manufacturing" decomposes at 348 °C.

Executive summary:

Approx. 2 g of substance were heated from 20 °C - 400 °C under isochoric conditions with a rate of 4,8 °C/min. Exothermia and increase in pressure should be determined.

Up to 400 °C exothermia could not be observed. The maximum pressure determined in this experiment was 166 bar at 348 °C. After cooling to 26 °C pressure was 140 bar.

The residue of the test substance was a black, charcoaled solid.

Description of key information

The test item was heated  under isochoric conditions.

At a temperature 348 °C the pressure increased to 169 bar.

Exothermia could not be observed.

Key value for chemical safety assessment

Temperature of decomposition (state purity):

348 °C