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Boiling point

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temperature of decomposition (state purity)
Type of information:
experimental study
Adequacy of study:
key study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
equivalent or similar to guideline
EU Method A.2 (Boiling Temperature)
GLP compliance:
Type of method:
differential scanning calorimetry
Specific details on test material used for the study:
Lot 201009MA2 solid
Key result
Atm. press.:
ca. 166 Bar
Decomp. temp.:
ca. 348 °C
The substance "By-product from Guanidinoacetic acid manufacturing" decomposes at 348 °C.
Executive summary:

Approx. 2 g of substance were heated from 20 °C - 400 °C under isochoric conditions with a rate of 4,8 °C/min. Exothermia and increase in pressure should be determined.

Up to 400 °C exothermia could not be observed. The maximum pressure determined in this experiment was 166 bar at 348 °C. After cooling to 26 °C pressure was 140 bar.

The residue of the test substance was a black, charcoaled solid.

Description of key information

The test item was heated  under isochoric conditions.

At a temperature 348 °C the pressure increased to 169 bar.

Exothermia could not be observed.

Key value for chemical safety assessment

Temperature of decomposition (state purity):
348 °C

Additional information