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water solubility
Data waiving:
study technically not feasible
Justification for data waiving:
Justification for type of information:
Due to the large variability caused by different carbon chain lengths at three individual positions, the individual components are expected to show different water solubility behaviour. This assumption is supported by data obtained during the determination of the log KOW of the test item using the HPLC method, as the log KOW is related to the water solubility of a substance. In total, 51 components were detected in the log KOW range < 1.1 up to > 9.95. Specific analytical monitoring of every component is therefore technically not possible.

During pre-tests performed under non-GLP conditions, it was planned to analyse the dis-solved organic carbon content of a slowly stirred aqueous fraction containing 1000 mg/L test item as a sum parameter. However, the test item dispersed immediately after contact with the water surface, so it was not possible to obtain clear samples. Centrifugation at 4000 g and filtration over membrane filters (0.2 µm PTFE) were not suitable for phase separation or sedimentation of the dispersed material.

Therefore, the determination of the water solubility of the test item X-21415 according to OECD 105 was considered technically not possible.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion