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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference Type:
study report

Materials and methods

Test guideline
according to guideline
OECD Guideline 105 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Reference substance name:
Docosan-1-ol, icosan-1-ol, octadecan-1-ol and their reaction products with betaine and ethanesulphonic acid
Docosan-1-ol, icosan-1-ol, octadecan-1-ol and their reaction products with betaine and ethanesulphonic acid
Test material form:
solid: bulk

Results and discussion

Water solubility
Key result
Water solubility:
> 53.23 - < 189.34 mg/L
Conc. based on:
test mat. (dissolved fraction)
20 °C
> 3.24 - < 3.94

Applicant's summary and conclusion

Executive summary:

The solubility of the test item in water was determined from the measured concentrations of DOC in the filtrated test solutions. The carbon content of the test item 74.51 % was used in the calculation of the test item concentration from the measured DOC concentration.

During the equilibration time in main test with the nominal loading range of 504 – 2508 mg/L, the concentration of DOC in the flasks 1A - C on days 1 – 3 were measured. Because of a difference of less than 15 % in the concentrations on days 2 and 3 and no upward tendency in the last three values, the test was finished on day 3.

The final measurement was performed as determination from flasks 2 – 6. DOC was measured via TOC analyser in the saturated aqueous solutions. The pH value in the flasks 2 – 6 lay in the range of 3.24 – 3.94.

No Tyndall effect (i.e. a laser beam was not scattered when transmitted through the liquid) could be observed indicating that no colloidal dispersed particles were present.

Linear dependency of the solubility on the amount of the test item (nominal load) was perceived in the flasks 1 – 6.


The solubility range for the tested nominal concentration 504 – 2508 mg/L is 53.23 – 189.34 mg/L, corresponding to a dissolved part of 7.78 ± 1.96 % of the test item relating to the nominal concentration of the test item (mean value).

No observations arousing doubts concerning the accuracy of the results and the validity of the study were made.