cyproconazole (ISO); (2RS,3RS;2RS,3SR)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

Other distribution data

Administrative data

Endpoint:

column leaching studies

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

26 Jan 1988

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1988

Report date:

1988

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: BBA Guidelines

Deviations:

yes

Remarks:

See section "Any other information on materials and methods incl. tables"

GLP compliance:

not specified

Type of study:

soil leaching

Test material

Test material information

Constituent 1

Reference substance name:

2-(4-chloro-phenyl)-3-cyclopropyl-1-[1,2,4]triazol-1-yl-butan-2-ol

Cas Number:

94361-06-5

Molecular formula:

C15H18ClN3O

IUPAC Name:

2-(4-chloro-phenyl)-3-cyclopropyl-1-[1,2,4]triazol-1-yl-butan-2-ol

Results and discussion

Any other information on results incl. tables

An overview of the results are provided in Table 2 and Table 3 below.

 

LEACHING TEST FINDINGS

The test substance was found to be immobile in the soil. The light soils Hatzenblihl and Flaach let penetrate only traces of the active ingredient in the range of 1 - 2 %, whereas the extreme light and sandy soil of Versuchsfeld did promote small amounts of about 4 % in the leachate. However, the soils Neuhofen, Witterswil and Strafanstalt containing more than 4.5 % organic matter, showed the absence of any radioactive compound above the limit of detection (0.5 % related to the applied dose). Such a behaviour of decreasing mobility in function of the increasing organic matter content is quite normal.

 

ADDITIONAL TEST FINDINGS

After elution with 400 mm of rain, most of the radioactivity remained in the upper part of the soil columns. About 90 to 95 % of the applied dose was found between 0 and 20 cm in the case of the light and sandy soil Versuchsfeld, between 0 and 15 cm in the case of the Hatzenblihl soil and in the upper 5 cm in the case of the Neuhofen soil. All lower layers did contain small or even negligible amounts of radioactivity.

 

Table 2. Results of recoveries.

	Spiking level	Recovery in the percolation
		water			organic extract
Versuchsfeld, Hatzenbtihl	about 16 μg	89-101 %			79-89%
Neuhofen, Witterswil	7.6 μg	89-95%			79-90%
Neuhofen, Witterswil	1.8 μg	93-95			92-96
Versuchsfeld, Hatzenbtihl	0.3 μg	96-103			91-100

 

Table 3. Leaching Behaviour of the test substance: Distribution of the Radioactivity in the Column.

Soils	Depth of soil layers			Amounts in the Various Layers
				in μg	in %
amount applied	0-30			14.92	100.0
Versuchsfeld (1.1 % org.m.)	0-5			3.60	24.1
	5-10			3.46	23.2
	10-15			3.52	23.6
	15-20			2.87	19.2
	20-25			0.99	6.6
	25-30			0.20	1.3
percolation water	-			0.54	3.6
total recovered	-			15.18	101.6
Hatzenbuhl (1.7 % org.m.)	0-5			5.95	39.9
	5-10			6.47	43.4
	10-15			1.69	11.3
	15-20			0.14	0.9
	20-25			0.06	0.4
	25-30			0.09	0.6
percolation water	-			≤ 0.30	≤ 2.0
total recovered	-			14.70	98.5
Neuhofen (4.5 % org.m.)	0-5			14.05	94.2
	5-10			0.29	1.9
	10-15			0.10	0.7
	15-20			0.05	0.3
	20-25			0.01	0.1
	25-30			0.02	0.1
percolation water	-			< 0.08	< 0.5
total recovered	-			14.52	97.2

Applicant's summary and conclusion

Conclusions:

In a column leaching study conducted according to BBA guidelines, the test substance was not mobile in agricultural soil and remained in the upper 5 to 20 cm layer of the soil. Therefore, contamination of the ground water is very unlikely to occur.

Executive summary:

The leaching behaviour of the test substance in six different soils (three BBA standard soils and three field soils) was investigated using the soil column technique according to BBA guidelines. An amount of the test substance corresponding to the dosage of about 80 g active ingredient per ha was added on top of the soil columns. Four volumes of 197 mL each of deionized water were then applied to the soil columns within four consecutive days. The percolation water from each soil column was collected and then analysed for its total radioactivity. The soil columns of Versuchsfeld, Hatzenblihl and Neuhofen were cut into six layers of 5 cm thickness and analysed for the remaining radioactivity.

The percolation water after elution with 400 mm rain contained radioactivity (related to applied dose) of ca. 4 % in very light and sandy soil (1.1 % organic matter.), 1 - 2 % in light soils (1.7 - 3.8 % organic matter.) and < 0.5 % in heavier soils (≥ 4.5 % organic matter). The radioactive compounds (mainly the test substance itself) were recovered in the upper 5 - 20 cm layers of the soil columns. Based on the findings, it is concluded that the leaching potential of the test substance in agricultural soils is very low. The contamination of the groundwater is very unlikely to occur.