cyproconazole (ISO); (2RS,3RS;2RS,3SR)-2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

Oxidising properties

Link to relevant study record(s)

Reference

Endpoint:

oxidising solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

29 Jun 1985 to 30 Jun 1985

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.17 (Oxidising Properties (Solids))

Version / remarks:

Dec 1992

GLP compliance:

yes (incl. QA statement)

Contact with:

powdered cellulose

Duration of test (contact time):

10 min

Key result

Sample tested:

reference mixture as specified

Remarks:

test substance/cellulose mixtures (ratio 10/90 to 60/40)

Parameter:

burning time of reaction over a distance of 200 mm

Remarks on result:

mixture does not ignite and burn

Sample tested:

reference mixture as specified

Remarks:

barium nitrate/cellulose 60:40 (w/w)

Parameter:

burning rate

Result:

3.39 mm/s

Remarks on result:

other: fastest burning rate of tested reference mixtures

Sample tested:

1:1 sample-to-cellulose ratio

Parameter:

burning rate

Result:

4.08 mm/s

Remarks on result:

result suspected of being a false positive

Sample tested:

reference mixture as specified

Remarks:

100 % cellulose

Parameter:

burning rate

Remarks on result:

other: does not ignite

Sample tested:

reference mixture as specified

Remarks:

barium nitrate/cellulose 70/30 (w/w)

Parameter:

burning time of reaction over a distance of 200 mm

Result:

40 s

Remarks on result:

sparking

Remarks:

Also smoking

REFERENCES

- A summary of the results of the reference mixtures is outlined in Table 1 (see below). The reference mixtures burned with an orange/green/yellow flame (height 1 - 7 cm, width 2 - 6 cm) emitting sparks and smoke. Combustion was observed through the whole pile. The fastest burning reference mixture was barium nitrate/cellulose 60/40 (w/w), with a burning rate of 3.39 mm/s.

TEST SUBSTANCE

- A summary of the results of the test substance/cellulose mixtures is outlined in Table 2 (see below). Combustion of the tested test substance/cellulose piles was observed at the surface of the piles. The burning rate of the test substance/cellulose mixtures was calculated by measuring the propagation of the flames on top of the pile:

- Ratio 10/90 to 30/70: The mixtures burned with a yellow flame (height: 1 - 4 cm, width: whole pile).

- Ratio 40/60: The mixtures burned with a yellow flame (height: 1 - 3 cm, width: whole pile) emitting black smoke.

- Ratio 50/50 to 80/20: The mixtures burned with a yellow flame (height: 3 - 6 cm, width: whole pile) emitting black smoke.

- Ratio 90/10: In contact with the ignition source, the test substance melted. The melted test substance burned with a yellow flame (height: 2 - 5 cm, width: 3 - 6 cm). After 10 minutes, the test was terminated.

Table 1 Burning rate versus reference composition

Barium nitrate/cellulose mixture (weight/weight ratio)	Burning time over 200 mm (s)	Burning rate (mm/s)
30/70	90	2.22
40/60	79	2.53
50/50	83	2.41
60/40	59	3.39

Table 2. Burning rate versus sample composition

Test substance/cellulose mixture (weight/weight ratio)	Burning time over 200 mm (s)	Burning rate (mm/s)
10/90	71	2.82
20/80	63	3.17
30/70	59	3.39
40/60	54	3.70
50/50	49	4.08
60/40	56	3.57
70/30	78	2.56
80/20	1351	1.14
90/10	**	**

** No burning time could be determined, because the mixture did not burn over 200 mm. After 10 minutes the burning distance was 15 cm.

ADDITIONAL TEST

The 100 % cellulose pile could not be ignited. The barium nitrate/cellulose mixture (ratio 70/30) burned and emitted smoke and sparks. The pile burned approximately 40 seconds. The test substance/cellulose mixtures (ratio 10/90 to 60/40) could not be ignited.

DISCUSSION

In the main study, the test substance/cellulose mixtures containing 20 – 60 % test substance had a burning rate comparable or faster than the fastest burning rate of the reference mixture.

In accordance to the criteria of the directive, the test substance may be concluded to have oxidising properties. But, the burning behaviour of the tested cellulose/test substance mixtures differed significantly from the burning behaviour of tested references (combustion of the cellulose/test substance piles was observed at the surface of the piles and combustion of the cellulose/barium nitrate was observed through the whole pile).

The burning behaviour of the cellulose/test substance mixtures is characteristic for non-oxidising substances. It was considered that in the main study a "false positive" effect was found. In the additional test it was found that the test substance/cellulose mixtures could not sustain a burning reaction in an inert atmosphere. From these results, it was concluded that in the main study a "false positive" effect was found. In conclusion, the test substance has no oxidising properties.

Interpretation of results:

GHS criteria not met

Conclusions:

The burning behaviour of the cellulose/test substance mixtures is characteristic for non-oxidising substances. It was considered that in the main study a "false positive" effect was found. In an additional test it was found that the test substance/cellulose mixtures could not sustain a burning reaction in an inert atmosphere. From these results, it was concluded that in the main study a "false effect" was found.

Executive summary:

The determination of the oxidising properties of test substance was performed in accordance EU method A.17 and in compliance with GLP On the main study, the test substance/cellulose mixtures containing 20 – 60 % test substance had a burning rate comparable or faster than the fastest In accordance to the criteria of the directive, the test substance may be concluded to have oxidising properties. But, the burning behaviour of the tested cellulose/test substance mixtures differed significantly from the burning behaviour of tested references (combustion of the cellulose/test substance· piles was observed at the surface of the piles and combustion of the cellulose/barium nitrate was observed through the whole pile). The burning behaviour of the cellulose/test substance mixtures is characteristic for non-oxidising substances. It was considered that in the main study a "false positive" effect was found. In an additional test it was found that the test substance/cellulose mixtures could not sustain a burning reaction in an inert atmosphere. From these results, it was concluded that in the main study a "false effect was found. The substance was not considered to be oxidising

Description of key information

The test substance is not an oxidising substance, EU Method A.17, Krips 1995.

Key value for chemical safety assessment

Oxidising properties:

non oxidising

Justification for classification or non-classification

Based on the available information, classification on oxidising properties is not warranted in accordance with EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation No. (EC) 1272/2008.