Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2002

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 112 (Dissociation Constants in Water)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
1,1,2,2,3,3,4,4,4-nonafluoro-N-methylbutane-1-sulfonamide
EC Number:
614-396-3
Cas Number:
68298-12-4
Molecular formula:
C5H4F9NO2S
IUPAC Name:
1,1,2,2,3,3,4,4,4-nonafluoro-N-methylbutane-1-sulfonamide

Results and discussion

Dissociating properties:
yes
Dissociation constant
No.:
#1
pKa:
7.52
Remarks on result:
other: Temperature and pH not provided

Applicant's summary and conclusion

Conclusions:
The pKa for MeFBSA was found to be 7.52.
Executive summary:

The pKa was determined for MeFBSA was determined using automated pH titration. The study was performed comparable to a guideline study but was not GLP compliant and was lacking sufficient documentation; therefore the study is considered reliable with restrictions.