7-ethoxy-4,6-difluoro-dibenzothiophen-3-ol

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2018-11-19 to 2018-11-22

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

GLP compliance:

no

Type of method:

differential scanning calorimetry

Key result

Melting / freezing pt.:

>= 151 - <= 155 °C

Atm. press.:

1 013.25 hPa

Decomposition:

no

Sublimation:

no

Melting point / melting range: DSC measurement

Three DSC measurements with a heating rate of 10 K/min showed an endothermal effect (melting) in the temperature range of 135 - 165 °C. The onset temperature was derived from the intersection of the tangent line with the highest slope of the endothermal peak with the baseline.

Melting point (DSC measurements)

Ident No.	Test item / mg	Starting temperature/ °C	Final test temperature / °C	Temperature range (endo-thermal) /°C	Onset (melting) /°C	Crucible	Observations after the measurement
38367	12.05	25	500	135-165	151.0	Aluminium with a hole	black residue, mass loss: 67%
38368	13.51	25	200	140-165	154.5	Aluminium with a hole	grey melt, no mass loss
38375	13.75	25	200	135-165	151.5	Aluminium with a hole	grey melt, no mass loss

 

The test item had a melting range of 151 - 155 °C.

Conclusions:

The test item melts in the range of 151 - 155 °C at 1013.25 hPa.

Executive summary:

A study was conducted according to OECD test guideline 102 and Regulation (EC) No 440/2008 method A. to determine the melting point of the test item using differential scanning calorimetry. The test item was weighed out into an aluminium crucible under an inert atmosphere (nitrogen). The test item and the reference were heated up from the starting temperature to the final temperature at a constant heating rate in a defined atmosphere (nitrogen). Open crucibles were used as containers for the test item and as empty reference crucible. Three DSC measurements with a heating rate of 10 K/min showed an endothermal effect (melting) in the temperature range of 135–165°C. The onset temperature of the three measurements were 151.0, 154.5 and 151.5 °C. Thus, it was concluded that the substance melts in the range 151 -155 °C at 1013.25 hPa.

Description of key information

The test item melts in the range of 151 - 155 °C at 1013.25 hPa (reference 4.2-1).

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

151 °C

Additional information

A study was conducted according to OECD test guideline 102 and Regulation (EC) No 440/2008 method A. to determine the melting point of the test item using differential scanning calorimetry. The test item was weighed out into an aluminium crucible under an inert atmosphere (nitrogen). The test item and the reference were heated up from the starting temperature to the final temperature at a constant heating rate in a defined atmosphere (nitrogen). Open crucibles were used as containers for the test item and as empty reference crucible. Three DSC measurements with a heating rate of 10 K/min showed an endothermal effect (melting) in the temperature range of 135–165 °C. The onset temperature of the three measurements were 151.0, 154.5 and 151.5 °C. Thus, it was concluded that the substance melts in the range 151 -155 °C at 1013.25 hPa.