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EC number: 946-188-6
CAS number: -
Under environmental conditions, the substance hydrolyses to glycoluril and glycoluril oligomers. Toxicity testing of the analogue substance cucurbituril hydrochloride hydrate has shown no toxicity to invertebrates (Daphnia) in an OECD guideline study at a nominal loading rate of 100 mg/L of the partially hydrolysed substance. The NOEC in a 21-day Daphnia reproduction study according to current OECD and EU guidelines was at 5 mg/L. In an algae toxicity study with both cucurbituril hydrochloride hydrate (not hydrolysed) and "reaction mass of cucurbituril, cucurbituril and cucurbituril", chuff and aggregated cells were observed at concentrations equal or greater than 0.10 mg/L. For the "reaction mass of cucurbituril, cucurbituril and cucurbituril", the algae study resulted in EC50(growth) and NOEC (growth) values of 1.8 and 0.32 mg/L, respectively. Given the physical incapacitation of the algae, the hydrolysis to non-toxic substances and the lack of effects in other aquatic species, suggest that the results reported in the algae study are due to artifacts and/or nutrient depletion and not relevant under environmental conditions. Studies over 11 days in marine diatoms did not result in any effects on the growth rate. Classification for aquatic toxicity is therefore not warranted.
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