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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 2019-01-08 to 2019-02-01
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
Study performed to current OECD guidelines with no significant deviations and run in OECD GLP certified lab.
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
1995
Deviations:
no
GLP compliance:
yes
Type of method:
flask method
Specific details on test material used for the study:
Purity: 99.7%
Batch No.: 80031745a
Key result
Water solubility:
7.63 g/L
Conc. based on:
test mat.
Loading of aqueous phase:
40 g/L
Incubation duration:
72 h
Temp.:
20 °C
pH:
>= 2.2 - <= 2.3
Details on results:
The water solubility of the test item at 20°C was 7.63 g/L.
The pH of the aqueous samples was 2.2 and 2.3.

Preliminary Test

The content of test item dissolved in the water sample was 7.44 g/L.

Main Study

The results for the samples taken at 24, 48 and 72 hours are given inTable below.

The maximum difference of the concentrations determined in the 24, 48 and 72 hour test samples was≤ 15%. Based on this, the water solubility of the test item is given as the mean value of the analyzed concentrations.

No test item was detected in the pretreated sample from the blank water mixture.


Water Solubility of the Test Item

Stirring time

[hours]

Analyzed concentration
[g/L]

Mean

[g/L]

Maximum difference
[%]

pH

 

 

 

 

 

24

7.57

7.63

1.5

2.2

 

 

 

 

 

48

7.68

 

 

2.2

 

 

 

 

 

72

7.63

 

 

2.3

 

 

 

 

 

Conclusions:
The water solubility of the test item at 20°C was 7.63 g/L. The pH of the aqueous samples was 2.2 and 2.3.
Executive summary:

The flask method was applied for the determination of the water solubility of the test item.

The water solubility of the test item at 20°C was 7.63 g/L. The pH of the aqueous samples was 2.2 and 2.3.

Description of key information

The water solubility of the test item at 20°C was 7.63 g/L. The pH of the aqueous samples was 2.2 and 2.3.

Key value for chemical safety assessment

Water solubility:
7.63 g/L
at the temperature of:
20 °C

Additional information

The flask method was applied for the determination of the water solubility of the test item.

The water solubility of the test item at 20°C was 7.63 g/L. The pH of the aqueous samples was 2.2 and 2.3.