Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: - | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- yes
- Remarks:
- The test item is an UVCB substance. Only one of the components was analytically determinable (602 Da). In order to reach a fully saturated test item solution very high test item concentrations 1 and 2 g) were applied.
- GLP compliance:
- yes
- Type of method:
- flask method
- Water solubility:
- 90.3 µg/L
- Conc. based on:
- other:
- Remarks:
- Only one component (602 Da) of the mixture was analytically determinable.
- Loading of aqueous phase:
- 1.077 g/L
- Incubation duration:
- 24 h
- Temp.:
- 20 °C
- pH:
- 5
- Water solubility:
- 221 µg/L
- Conc. based on:
- other:
- Remarks:
- Only one component (602 Da) of the mixture was analytically determinable.
- Loading of aqueous phase:
- 2.1 g/L
- Incubation duration:
- 24 h
- Temp.:
- 20 °C
- pH:
- 5
- Details on results:
- Despite the application of very high test item loading (1 and 2 g per liter) the solubility of the only analytically determinable component (602 Da) varied depending upon the loaded amount.
- Conclusions:
- The highest determined water solubility for the component tested (602 Da) was found to be 221 ug/L.
- Executive summary:
Only one component of the mixture was analytically determinable. The solubility of this component varied with the loading of the substance, despite the fact that the loading was orders of magnitude higher than the actually determined water solubility.
As a conservative assumption the highest determined water solubility was taken as key value.
Reference
Description of key information
The highest determined water solubility was found to be 221 ug/L.
Key value for chemical safety assessment
- Water solubility:
- 221 µg/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
