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EC number: 825-760-8 | CAS number: 39290-95-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicological Summary
- Administrative data
- Workers - Hazard via inhalation route
- Workers - Hazard via dermal route
- Workers - Hazard for the eyes
- Additional information - workers
- General Population - Hazard via inhalation route
- General Population - Hazard via dermal route
- General Population - Hazard via oral route
- General Population - Hazard for the eyes
- Additional information - General Population
Administrative data
Workers - Hazard via inhalation route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Workers - Hazard via dermal route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
Workers - Hazard for the eyes
Local effects
- Hazard assessment conclusion:
- no hazard identified
Additional information - workers
Acute / short-term exposure - systemic and local effects
Inhalation:
No relevant data are available that might indicate any systemic or local adverse effect after acute/short-term exposure to tungsten zirconium oxide. No systemic or local effects have been observed in the available short-term toxicological study with the read across substance zirconium dioxide, the main component in the crystal lattice of tungsten zirconium oxide, up to the maximal technically achievable concentration. Consequently, no DNELs needs to be derived.
However, national occupational exposure limits for zirconium and tungsten compounds should be respected where relevant. The STEL (Short Term Exposure Limit, 15 minutes) for both zirconium and tungsten is typically 10 mg/m³.
Dermal:
No relevant data are available that might indicate any systemic or local adverse effect after acute/short-term dermal exposure to tungsten zirconium oxide. Therefore, no DNELs are derived for this route of exposure.
Long-term exposure - systemic and local effects
Inhalation:
No data are available that might indicate any systemic or local adverse effect after long-term exposure to tungsten zirconium oxide. No systemic or local adverse effects have been observed in the available studies with zirconium dioxide, the main component in the crystal lattice of tungsten zirconium oxide. Therefore no long-term DNELs needs to be derived after inhalation exposure.
However, national occupational exposure limits for zirconium and tungsten compounds should be respected where relevant. The 8-h Time Weighted Average (TWA) Occupational Exposure Limit (OEL) for both zirconium and tungsten is typically 5 mg/m³. Therefore, although it is considered reasonable not to derive DNELs for tungsten zirconium oxide, this exposure limit should be respected where relevant.
Dermal:
No data are available that might indicate hazardous systemic or local effects after long-term dermal exposure. Therefore, no long-term DNELs are derived for this route of exposure.
Hazard for the eyes
Tungsten zirconium oxide was found not to to be an eye irritant (in vitro testing).
General Population - Hazard via inhalation route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
General Population - Hazard via dermal route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
General Population - Hazard via oral route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
General Population - Hazard for the eyes
Local effects
- Hazard assessment conclusion:
- no hazard identified
Additional information - General Population
Acute / short-term exposure - systemic and local effects
Inhalation:
No relevant data are available that might indicate any systemic or local adverse effect after acute/short-term exposure to tungsten zirconium oxide. No systemic or local effects have been observed in the available short-term toxicological study with the read across substance zirconium dioxide, the main component in the crystal lattice of tungsten zirconium oxide, up to the maximal technically achievable concentration. Consequently, no DNELs need to be derived.
Dermal:
No relevant data are available that might indicate any systemic or local adverse effect after acute/short-term dermal exposure to tungsten zirconium oxide. Therefore no DNELs can be derived for this route of exposure.
Oral:
Based on available experimental data, there are no acute toxic effects leading to classification, hence no acute/short-term DNEL (systemic effects) needs to be derived.
Long-term exposure - systemic and local effects
Inhalation:
Based on the available data and the same argumentation as for workers, no long-term DNELs need to be derived for the general population.
Dermal route:
Based on the same argumentation as for workers (no long-term dermal toxicity data available, no adverse effects observed in oral and inhalation repeated dose toxicity studies), no long-term DNELs need to be derived for the general population.
Oral:
No oral repeated dose toxicity studies are available for zirconium dioxide, however, read across can be performed from two studies with zirconium basic carbonate (another insoluble zirconium compound) and zirconium acetate (a 'water soluble' zirconium compound). In these studies, no adverse effects were observed up to the highest (limit) test dose. Therefore, it is not considered necessary to derive a long-term DNEL.
Further argumentation on read across and the overall extremely low potential of zirconium compounds for causing toxicity is given in the read across justification attached to Section 13 of IUCLID.
Hazards for the eyes
Tungsten zirconium oxide was concluded not to be hazardous for eyes.
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