Registration Dossier
Registration Dossier
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EC number: 946-856-7 | CAS number: -
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 02/13/2019 - 02/25/2019
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - Shake Flask Method)
- Principles of method if other than guideline:
- the test item is poorly soluble in n-octanol, so 1 % dimethyl sulfoxide is added.
- GLP compliance:
- no
- Type of method:
- flask method
- Partition coefficient type:
- other: octanol-water with 1 % dimethyl sulfoxide
Test material
- Test material form:
- solid: particulate/powder
Constituent 1
Study design
- Analytical method:
- photometric method
Results and discussion
Partition coefficient
- Type:
- Pow
- Remarks on result:
- not determinable because of methodological limitations
- Details on results:
- The calibration solutions and the sample solutions showed different spectra and colours. In addition, deviating results of the duplicate determinatins were found. Thus it can be assumed that the test item dissolved only partially or a reaction of the test item occurred. Therefore the concentration of the test item in the octanol phase could not be calculated.
Applicant's summary and conclusion
- Conclusions:
- Further calculation of the partition coefficient was not possible
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