Registration Dossier
Registration Dossier
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EC number: 294-510-2 | CAS number: 91723-07-8 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Hibiscus esculentus, Malvaceae.
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
An Ames assay was started. Due to contamination of the test substance, also after sterilisation, the test substance is not suitable for the bacterial reverse mutation assay. Due to contaminations of the test substance observed in the 1st Experiment an evaluation of the experiment was not possible. Different attempts were performed to sterilize the test substance (e.g. use of UV light and/or sterilization in 70% ethanol). However, none of the tested possibilities were successful. Therefore, the test substance is not suitable for the bacterial reverse mutation assay.
Information on genetic toxicity can be obtained based on the chemical composition of the substance. The substance is the residues of an extraction process of Hibiscus seed. The analytical report revealed that the substance contains water, ash, proteins, fat, dietary fibers and carbohydrates. It is not assumed that these substance could cause genetic toxicity. As a consequence, the substance is not classified with regard to genetic toxicity.
Additional information
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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