Registration Dossier

Diss Factsheets

Physical & Chemical properties

Vapour pressure

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
07/07/17-20/06/18
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
GLP run to current guidelines.
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: vapour pressure balance
Specific details on test material used for the study:
Identification: Reaction product of 2,3-epoxypropyl neodecanoate and Benzenesulfonic acid, C10-13-sec-alkyl derivatives
Appearance/Physical state: Brown liquid
Batch: P718261998
Purity: 97.7%
Expiry date: 01 June 2018
Storage conditions: Room temperature in the dark
Key result
Test no.:
#1
Temp.:
25 °C
Vapour pressure:
<= 0.014 Pa

Recorded temperatures, mass differences and the resulting calculated values of vapor pressure are shown below.

Table 1: Results for Run 8

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (μg)

Mass Difference (kg)

Vapor Pressure (Pa)

Log10Vp

80

353.15

0.002832

35.64

3.564e-08

0.04948

-1.30557

81

354.15

0.002824

34.35

3.435e-08

0.04769

-1.32157

82

355.15

0.002816

36.74

3.674e-08

0.05100

-1.29243

83

356.15

0.002808

37.04

3.704e-08

0.05142

-1.28887

84

357.15

0.002800

35.64

3.564e-08

0.04948

-1.30557

85

358.15

0.002792

35.54

3.554e-08

0.04934

-1.30680

86

359.15

0.002784

28.85

2.885e-08

0.04005

-1.39740

87

360.15

0.002777

36.34

3.634e-08

0.05045

-1.29714

88

361.15

0.002769

37.94

3.794e-08

0.05267

-1.27844

89

362.15

0.002761

36.44

3.644e-08

0.05059

-1.29594

90

363.15

0.002754

36.34

3.634e-08

0.05045

-1.29714

No statistical analysis is given due to the nature of the plot of Log10 Vp versus K-1.

Table 2: Results for Run 9

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (μg)

Mass Difference (kg)

Vapor Pressure (Pa)

Log10Vp

80

353.15

0.002832

34.15

3.415e-08

0.04741

-1.32413

81

354.15

0.002824

35.74

3.574e-08

0.04962

-1.30434

82

355.15

0.002816

29.95

2.995e-08

0.04158

-1.38112

83

356.15

0.002808

34.65

3.465e-08

0.04810

-1.31785

84

357.15

0.002800

37.74

3.774e-08

0.05239

-1.28075

85

358.15

0.002792

34.85

3.485e-08

0.04838

-1.31533

86

359.15

0.002784

35.24

3.524e-08

0.04892

-1.31051

87

360.15

0.002777

33.55

3.355e-08

0.04658

-1.33180

88

361.15

0.002769

31.35

3.135e-08

0.04352

-1.36131

89

362.15

0.002761

37.54

3.754e-08

0.05212

-1.28300

90

363.15

0.002754

35.84

3.584e-08

0.04976

-1.30312

No statistical analysis is given due to the nature of this plot.

Table 3: Results for Run 10

Temperature (ºC)

Temperature (K)

Reciprocal Temperature (K-1)

Mass Difference (μg)

Mass Difference (kg)

Vapor Pressure (Pa)

Log10Vp

80

353.15

0.002832

33.15

3.315e-08

0.04602

-1.33705

81

354.15

0.002824

31.95

3.195e-08

0.04435

-1.35311

82

355.15

0.002816

35.24

3.524e-08

0.04892

-1.31051

83

356.15

0.002808

34.85

3.485e-08

0.04838

-1.31533

84

357.15

0.002800

28.95

2.895e-08

0.04019

-1.39588

85

358.15

0.002792

32.75

3.275e-08

0.04547

-1.34228

86

359.15

0.002784

28.56

2.856e-08

0.03965

-1.40176

87

360.15

0.002777

33.85

3.385e-08

0.04699

-1.32799

88

361.15

0.002769

34.45

3.445e-08

0.04783

-1.32030

89

362.15

0.002761

33.25

3.325e-08

0.04616

-1.33573

90

363.15

0.002754

34.45

3.445e-08

0.04783

-1.32030

No statistical analysis is given due to the nature of the plot of Log10Vp versus K-1.

The test item did not change in appearance under the conditions used in these determinations and no statistical analyses were performed because the balance readings were too low and variable for a line of best fit to have any meaning. Instead it was considered more appropriate to impose a regression slope on a chosen data point to provide an estimate of the maximum value for the vapor pressure at 25 ºC. Run 10 was chosen because the sample had been under vacuum for the longest time so degassing would have been the most complete and the reading at 82 ºC (355.15 K) was chosen because this is the data point which gives the highest estimated vapor pressure at any given temperature when a slope of –1000 K is imposed upon it.

The value of –1000 K is an in-house value and is the shallowest slope observed whilst determining the vapor pressure on a wide range of samples using the vapor pressure balance method. Extrapolation to 25 ºC gave a vapor pressure of 1.42 x 10-2 Pa which has been taken as a maximum for this material.

Conclusions:
The vapor pressure of 'Reaction product of 2,3-epoxypropyl neodecanoate and Benzenesulfonic acid, C10-13-sec-alkyl derivatives' has been determined to be ≤1.42 x 10^-2 Pa at 25 °C, using the vapor pressure balance method, designed to be compatible with Method A.4 Vapour Pressure of Commission Regulation (EC) No 440/2008 of 30 May 2008, and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.
Executive summary:

The vapor pressure of 'Reaction product of 2,3-epoxypropyl neodecanoate and Benzenesulfonic acid, C10-13-sec-alkyl derivatives' has been determined to be ≤1.42 x 10-2 Pa at 25 °C, using the vapor pressure balance method, designed to be compatible with Method A.4 Vapour Pressure of Commission Regulation (EC) No 440/2008 of 30 May 2008, and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.

Description of key information

The vapor pressure of 'Reaction product of 2,3-epoxypropyl neodecanoate and Benzenesulfonic acid, C10-13-sec-alkyl derivatives' has been determined to be ≤1.42 x 10-2 Pa at 25 °C, using the vapor pressure balance method, designed to be compatible with Method A.4 Vapour Pressure of Commission Regulation (EC) No 440/2008 of 30 May 2008, and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.

Key value for chemical safety assessment

Vapour pressure:
0.014 Pa
at the temperature of:
25 °C

Additional information

The vapour pressure (above) is taken as a maximum value for this material.

Categories Display