reaction product of toluenediisocyanate ( reaction mass of isomers: 65 % 2,4- and 35 % 2,6-diisocyanate) and aniline (molarratio 1:2)

Flammability

Link to relevant study record(s)

Reference

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

01 May 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.10 (Flammability (Solids))

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Test procedure:

burning rate test: preliminary screening test

Remarks on result:

substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period

The test item was observed to ignite after 5 seconds of application of the burner flame. The flame propagated along 200 mm of the train in a total of 5 minutes and 6 seconds. As this was longer than the limit of 4 minutes, the test item was not considered to be highly flammable.

Interpretation of results:

not classified based on GHS criteria

Conclusions:

The test item was found to be not highly flammable in the preliminary test, and therefore, a defintive test was not required.

Executive summary:

The flammability of the test item was investigated in an EC Method A.10 study. The study is a GLP compliant, guideline experimental study and is fully acceptable for assessment of this endpoint.

The test item was found to be not highly flammable.

Description of key information

The test item was found to be not highly flammable.

Key value for chemical safety assessment

Flammability:

not classified

Additional information

The flammability of the test item was investigated in two EC Method A.10 studies (Dunning 2018a and Dunning 2018b). The test item was found to be not highly flammable; the study is a GLP compliant, guideline experimental study and is fully acceptable for assessment of this endpoint (Dunning 2018b).

In the study Dunning 2018a, in the preliminary test the test item sub was observed to ignite and burn at point of contact with the burner flame. The flame propagated along 200 mm of the train in a total of 2 minutes and 4 seconds. As this was shorter than the limit of 4 minutes, the test item was considered to be highly flammable. Further definitive testing would normally be performed but the sponsor believed there may have been excess solvent on the test item after isolation from the grease-base. Therefore, after discussions with the CRO and the sponsor it was decided to isloated a new batch of the test item. In the second study, it was ensured all excess solvent was removed and the test item was found not to be highly flammable (Dunning 2018b).

Justification for classification or non-classification

Based on the results of a GLP-compliant study following a standard test guideline, the substance does not require classification as a flammable solid.