Registration Dossier
Registration Dossier
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EC number: 211-779-3 | CAS number: 695-12-5
Endpoint summary
Administrative data
Description of key information
According to REACH Annex VII/VIII column 2 it is not necessary to conduct acute toxicity studies because the target substance is classified as corrosive to the skin. Nevertheless, available data from the literature is presented. Based on the results from an acute oral toxicity study, the oral LD50 can be considered to be greater than 2000 mg/kg bw in rat and mouse and the LC50 for rats can be considered to be 20.5 mg/mL and 13.7 mg/L for mice. Due to limited information presented regarding methodology, the available data cannot be used for classification and should be considered only as supporting data.
According to the ECHA Guidance on information requirements and chemical safety assessment Part E: Risk Characterisation (Version 3, May 2016), substances classified for Skin Corrosion Category 1B are allocated to the moderate hazard band.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
According to REACH Annex VII/VIII column 2 it is not necessary to conduct acute toxicity studies because the target substance is classified as corrosive to the skin. Nevertheless, available data from the literature is presented. Based on the results from an acute oral toxicity study, the oral LD50 can be considered to be greater than 2000 mg/kg bw in rat and mouse and the LC50 for rats can be considered to be 20.5 mg/mL and 13.7 mg/L for mice. Due to limited information presented regarding methodology, the available data cannot be used for classification and should be considered only as supporting data.
According to the ECHA Guidance on information requirements and chemical safety assessment Part E: Risk Characterisation (Version 3, May 2016), substances classified for Skin Corrosion Category 1B are allocated to the moderate hazard band.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
