Reaction mass of N-butylphthalimide and N-sec-butylphthalimide and N-propylphthalimide

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

02 June 2016 - 16 June 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

27 July 1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7200 (Melting Point / Melting Range)

Version / remarks:

1998

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Key result

Melting / freezing pt.:

> 2.6 - < 3.7 °C

Atm. press.:

> 1 006 - < 1 008 hPa

Decomposition:

yes

Remarks:

Decomposition energy of -270 J/g

Decomp. temp.:

> 380 - < 470 °C

During the cooling phase an exothermic effect could be observed in the temperature range of approximately -10 to -30 °C, which can be assigned to the freezing of the test item. In the subsequent heating phase an endothermic effect was detected inthe temperature range of -10 to 20 °C, which can be assigned to the melting of the test item. As the onset temperatures in both tests deviate by more than 0.5 K from their mean value of 3.12 °C, the test item has a melting range of 2.6 to 3.7 °C.

Due to the low energy of the melting peak, the melting of the test item was verified. A small amount of the test item in a test tube was cooled down to -24.5 °C in a freezer. At this temperature the test item was solid. For warming up, the frozen sample was placed in a refrigerator at 3.5 °C. After eight hours the sample was still frozen. After 10 minutes at room temperature the test item was liquefied. Therefore the melting point in the DSC-measurement was confirmed.

No.	Sample weight / mg	Onset of Effect / °C	Range of effect / °C	Weight loss / mg	Atmospheric pressure / hPa	Remark
PN11224	14.49	3.65 303.09	-10 – 20 (endo) 120 – 320 (endo)	14.49	1007.9	Figure 1
PN11234	16.70	2.59 302.18	0 – 20 (endo) 120 – 320 (endo)	16.58	1005.9	Figure 2

Conclusions:

The test Item reaction mass of N-butylphthalimide and N-sec-phthalimide and N-propylphthalimide has a melting range of 2.6 to 3.7 °C at atmospheric pressure (1006 or 1008 hPa, respectively ) as determined by differential scanning calorimetry according to Regulation EC No. 440/2008 Method A.1. and OECD Test Guideline 102 (1995).

Executive summary:

The test item reaction mass of N-butylphthalimide and N-sec-phthalimide and N-propylphthalimide has a melting range of 2.6 to 3.7 °C at atmospheric pressure (1006 or 1008 hPa, respectively) as determined by differential scanning calorimetry according to Regulation EC No. 440/2008 Method A.1. and OECD Test Guideline 102 (1995).

Description of key information

The test item has a melting range of 2.6 to 3.7 °C at atmospheric pressure (1006 or 1008 hPa, respectively) as determined by differential scanning calorimetry according to Regulation EC No. 440/2008 Method A.1. and OECD Test Guideline 102 (1995).

Key value for chemical safety assessment

Additional information

Melting point range of 2.6 to 3.7 °C.