Amines, C12-16 alkyl dimethyl, reaction products with ethyl chloroacetate, 2-(2-aminoethylamino)ethanol and 2-propenoic acid

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

GLP compliance:

yes

Type of method:

effusion method: vapour pressure balance

Temp.:

20 °C

Vapour pressure:

< 1 Pa

Results of first measurement

Temperature [°C]	Vapour pressure^1)[hPa]
20	0.00406
30	0.003635
40	0.005514
50	0.006477
60	0.007103
70	0.005577
80	0.006849

¹⁾Mean value of triplicate measurements

Probably the sample contained too much resuidual moisture. During the measurement the water content decreased and the vapour pressure did not increase significantly despite the increasing temperature. The measurement was aborted at 80 °C due to failure of the instrument.

Results of second measurement

Temperature [°C]	Vapour pressure^1)[hPa]
20	0.001215
30	0.001627
40	0.001428
50	0.000698
60	0.000248
70	0.000264
80	0.000316
100	0.000484
120	0.003239
140	0.010311
160	^2)

¹⁾Mean value of triplicate measurements

²⁾Data could not be saved

Due to the extensive degassing procedure the sample contained not so much residual moisture. Despite increasing temperature the vapour pressure decreased in the range of 30 to 70 °C, but strong increase of the vapour pressure above 100 °C. The sample showed a foamed appearance after the emasurement.

Results of third/fourth measurement

Temperature [°C]	Vapour pressure^1)[hPa]
20	No signal
30	No signal
50	No signal
70	0.000355
90	0.000378
110	0.000439
130	0.006055
150	0.022932
170	Out of range
70	0.001612
90	0.001767
110	0.002437

¹⁾Mean value of triplicate measurements

The sample was degassed in the measuring system for 6 days at room temperature. At lower temperatures no signal was detected. In the medium temperature range the vapour pressure was measured close to the data of the second measurement. At 170 °C the signal was too large for the system. Maybe decomposition starts at this temperature which would be in accordance with thermogravimetric measurements.

The measurements in the medium temperature range were repeated subsequently from 70 °C to 110 °C.

Conclusions:

The vapor pressure data between 100 and 160 °C seem to be most representative of the pure test item. At lower temperatures residual moisture determines the vapour pressure. Extrapolation of the vapour pressure data > 100 °C to 20 °C gives a calculated data of approximately 40 µPa. However, due to the analytical range of the system and own experience it is concluded that the vapour pressure of the test item is < 1 Pa at 20 °C.

Executive summary:

The vapour pressure of the test substance was determined according to the OECD Guideline 104 by means of the effusion method using a vapour pressure balance. Vapour pressure was determined in four measurements in a temperature range from 20 to 160 °C. The test sample obviously contained a significant level of residual moisture. At lower temperatures residual moisture determines the vapour pressure. Extrapolation of the vapour pressure data > 100 °C to 20 °C gives a calculated data of approximately 40 µPa. However, due to the analytical range of the system and own experience it is concluded that the vapour pressure of the test item is < 1 Pa at 20 °C.

Description of key information

Extrapolation of the vapour pressure data > 100 °C to 20 °C gives a calculated data of approximately 40 µPa for the source substance. However, due to the analytical range of the system and own experience it is concluded that the vapour pressure of the test item is < 1 Pa at 20 °C.

The same result can be expected for the target substance.

Key value for chemical safety assessment

Vapour pressure:

0 Pa

at the temperature of:

20 °C