Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 904-139-6 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
QSAR modelling of the components of the substance, monoethyl, diethyl and triethyl citrate do not indicate strtuctural elements leading to protein binding and potential sensitisation.
Data are available on one constituent of the substance, triethyl citrate. A guinea pig maximisation test found strong evidence of the potential for sensitisation but a human repeat insult patch test found no evidence of sensitisation occurring in humans. The substance was judged to be a non-sensitiser based on the criteria established by the FDA for sensitisation of human subjects
Justification for classification or non-classification
Based on the available data the substance does not require to be classified and labelled according to Regulation 1272/2008/EC (CLP) or Directive 67/548/EEC (DSD).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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